pentobarbital will lessen the extent or influence of paclitaxel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.
Keep an eye on Intently (1)pentobarbital will lessen the extent or result of glecaprevir/pibrentasvir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the level or influence of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will reduce the level or result of amlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will reduce the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will minimize the extent or result of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Think about an increase in cannabidiol dosage (depending on medical response and tolerability) when coadministered with a powerful CYP3A4 inducer.
pentobarbital will lessen the level or result of zaleplon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
pentobarbital will decrease the extent or influence of nimodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.
Either raises toxicity of one other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Profound sedation, respiratory despair, coma, and Demise may possibly outcome if coadministered. Reserve concomitant prescribing of these medicine in patients for whom other treatment alternatives are insufficient. Restrict dosages and durations into the minimal necessary. Observe closely for indications of respiratory melancholy and sedation.
pentobarbital will lessen the level or effect of lapatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
sodium oxybate and pentobarbital equally enhance sedation. click here Steer clear of or Use Alternate Drug. Limit use to people for whom substitute cure choices are inadequate
Reserve concomitant prescribing of those medication in people for whom other treatment method choices are insufficient. Restrict dosages and durations into the least expected. Watch closely for indications of respiratory despair and sedation.
pentobarbital will reduce the extent or result of etonogestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Therapy need to be administered with warning, if in the least, to clients who are mentally frustrated, have suicidal tendencies, or heritage of drug abuse